Interfacing Chemical Biology and Drug Discovery

RICT 2021

56th International Conference on Medicinal Chemistry
56èmes Rencontres Internationales de Chimie Thérapeutique

 Virtual Event    July 7-9, 2021

Programme

Indicated times are in CEST timezone.




09:45

Start of sessions

RICT Opening
RICT Opening
09:45
Opening Ceremony
Prof. Rebecca DEPREZ-POULAIN
UNIVERSITY OF LILLE / INSTITUT PASTEUR OF LILLE, Lille, France
Prof. Sebastien PAPOT
SCT & UNIVERSITY OF POITIERS, Poitiers, France
10:00

Start of sessions

Chemical Biology and Target validation
Chemical Biology and Target validation
Session Chair
Dr Boris VAUZEILLES
INSTITUT DE CHIMIE DES SUBSTANCES NATURELLES, Gif-sur-Yvette, France
10:00
Expanding the Genetic Code - Chemistry in Living Systems (PL01)
Prof. Kathrin LANG
ETH ZURICH, Zurich, Switzerland
10:30
Ligand-Directed Labeling of Endogenous Proteins in Live Cells (PL02)
Prof. Itaru HAMACHI
KYOTO UNIVERSITY, Kyoto, Japan
11:00
Networking & Exhibition break
Session Chair
Dr Frédéric SCHMIDT
INSTITUT CURIE, Paris, France
11:30
Bioorthogonal Protein Activation in Living Systems (PL03)
Prof. Peng CHEN
PEKING UNIVERSITY, Beijing, China
12:00
Chemical Biology Tools for Enlightening Therapies (IL01)
Prof. Olalla VÁZQUEZ
PHILIPPS-UNIVERSITÄT MARBURG, Marburg, Germany
12:20
End of morning session
13:00
Poster Session 1
Exhibition
Networking
Poster Session 1
Exhibition
Networking
15:00

Start of sessions

New Modalities in Drug Discovery
New Modalities in Drug Discovery
Session Chair
Prof. Mélanie ETHEVE-QUELQUEJEU
UNIVERSITÉ DE PARIS, Paris, France
15:00
Chemical Targeting of DNA and Histone Methylationto Reprogram Cells in Human Diseases: Challenges and Future Perspectives (PL04)
Dr Paola B. ARIMONDO
INSTITUT PASTEUR - CNRS, Paris, France
15:30
The Second Dimension of the Genetic Code (PL05)
Prof. Thomas CARELL
LUDWIG-MAXIMILIANS-UNIVERSITY, München, Germany
16:00
Networking & Exhibition break
Session Chair
Dr Maria DUCA
UNIVERSITY OF CÔTE D'AZUR, Nice, France
16:30
From Simple to Complex in Natural Product Chemistry: Bio-Inspired Strategies to Escape “Flatland” (PL06)
Prof. Erwan POUPON
PARIS-SACLAY UNIVERSITY, Châtenay-Malabry, France
17:00
Taming Random Conjugation: a General Approach for Equimolar Linking of Proteins and Payloads (IL02)
Dr Sergii KOLODYCH
SYNDIVIA, Strasbourg, France
17:20
End of afternoon session
10:00

Start of sessions

Case Studies and Disclosures
Case Studies and Disclosures
Session Chair
Dr Pascal GEORGE
SCT & SCIENTIFIC EXPERT & ADVISER IN DRUG DESIGN AND DEVELOPMENT, Longvilliers, France
10:00
Steroid Sulfatase Inhibition: from Concept to Clinical and Beyond (PL07)
Prof. Barry POTTER
UNIVERSITY OF OXFORD, Oxford, United Kingdom
10:30
Recent Advances In Breast Cancer Treatment: Discovery of Amcenestrant (SAR439859), An Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) to Treat ER+ Breast Cancers (PL08)
Dr Youssef EL AHMAD
SANOFI, Vitry Sur Seine, France
11:00
Networking & Exhibition break
Session Chair
Dr Olivier MIRGUET
EVOTEC, Toulouse, France
11:30
Daridorexant - a Dual Orexin Receptor Antagonist (PL09)
Dr Christoph BOSS
IDORSIA PHARMACEUTICALS LTD, Allschwil, Switzerland
12:00
Anti-Virulence Agent to Treat S. Aureus Infections (IL03)
Dr Alessia MICHELOTTI
BIOVERSYS AG, Basel, Switzerland
12:20
End of morning session
13:00
Poster Session 2
Exhibition
Networking
Poster Session 2
Exhibition
Networking
15:00

Start of sessions

New Tools for Therapeutic Innovation
New Tools for Therapeutic Innovation
Session Chair
Prof. Sébastien LECOMMANDOUX
LCPO, ENSCBP-BORDEAUX INP, Pessac, France
15:00
Multi-Target-Directed Ligands to Combat Neurodegenerative Diseases: All-In-One and One-For-All (PL10)
Prof. Maria Laura BOLOGNESI
UNIVERSITY OF BOLOGNA, Bologna, Italy
15:30
Converting Drug Delivery Technologies into Drugs in Unmet Medical Needs (PL11)
Prof. Jean-Christophe LEROUX
ETH ZÜRICH, Zürich, Switzerland
16:00
Networking & Exhibition break
16:30

Start of sessions

Prize Ceremony - Paul Ehrlich Prize
Prize Ceremony - Paul Ehrlich Prize
16:30
Paul Ehrlich Prize Ceremony
Dr Susana CONDE CEIDE
JANSSEN, Toledo, Spain
Dr Dominique LESUISSE
SCT & SANOFI, Chilly-Mazarin, France
16:40
Paul Ehrlich Award Lecture - 30 Years of Molecular Glues: Controlling Cell Circuitry in Biology and Medicine (PL12)
Prof. Stuart SCHREIBER
HARVARD UNIVERSITY, Cambridge, United States
17:25
End of afternoon session
10:00

Start of sessions

Drugging the Undruggable
Drugging the Undruggable
Session Chair
Dr Gilles GUICHARD
CBMN & IECB, UNIVERSITY OF BORDEAUX, CNRS, BORDEAUX INP, Pessac, France
10:00
Targeting Protein-Protein Interactions in Receptor Complexes (PL13)
Prof. Kristian STROMGAARD
UNIVERSITY OF COPENHAGEN, Copenhagen, Denmark
10:30
Selecting Targets to Harness the Therapeutic Opportunities Afforded by PROTAC-mediated Protein Degradation (PL14)
Dr John HARLING
GLAXOSMITHKLINE, Stevenage, United Kingdom
11:00
Networking & Exhibition break
Session Chair
Prof. Dominique BONNET
CNRS-UNIVERSITY OF STRASBOURG, Illkirch, France
11:30
Proteomimetics as Inhibitors of Transcription Factor Complexes (PL15)
Prof. Tom GROSSMANN
VU UNIVERSITY AMSTERDAM, Amsterdam, The Netherlands
12:00
Drugging KRAS with Medchem 2.0 (PL16)
Dr Darryl MCCONNELL
BOEHRINGER INGELHEIM RCV, Vienna, Austria
12:30
End of morning session
13:00
Poster Session 3
Exhibition
Networking
Poster Session 3
Exhibition
Networking
15:00

Start of sessions

Success Stories
Success Stories
Session Chair
Prof. Philippe BARTHELEMY
UNIVERSITY OF BORDEAUX, INSERM, Bordeaux, France
15:00
Identification of the Potent, Highly Selective and Orally Bioavailable ATR Inhibitor BAY 1895344 (PL17)
Dr Franz VON NUSSBAUM
NUVISAN ICB GMBH, Berlin, Germany
15:30
Biomimetic Chemistry of Human RNAi Therapeutics (PL18)
Dr Muthiah MANOHARAN
ALNYLAM PHARMACEUTICALS, Cambridge, United States
16:00
Networking & Exhibition break
16:30

Start of sessions

Prize Ceremony - Pierre Fabre Award Lecture
Prize Ceremony - Pierre Fabre Award Lecture
16:30
Pierre Fabre Award Ceremony
Prof. Sebastien PAPOT
SCT & UNIVERSITY OF POITIERS, Poitiers, France
16:40
Pierre Fabre Award Lecture - Metal Complexes in Medicinal Chemistry (PL19)
Dr Gilles GASSER
CHIMIE PARISTECH, PSL UNIVERSITY, Paris, France
17:25
Closing Remarks
Prof. Rebecca DEPREZ-POULAIN
UNIVERSITY OF LILLE / INSTITUT PASTEUR OF LILLE, Lille, France
17:30
End of RICT 2021